Anti-ceh-10

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1: 64,000 confirmed by ELISA, 3. WB positive with the immunogen protein (not applicable for synthetic peptide). Applications: ELISA, WB (positive for the recombinant immunogen protein/peptide). Buffer: Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Protein function: Transcription factor (PubMed:15177025). Binds to a sequence motif, 5'-TTATTGGCTTCGTTAA-3', which may be involved in AIY interneuron function, in the regulatory elements of target genes, binding is more efficient, in vitro, together with LIM/homeobox protein ttx-3 (PubMed:15177025). Required for larval development and for cell fate specification and migration of CAN neurons (PubMed:11493519, PubMed:2361334, PubMed:9475729). Required for generation, or placement, and differentiation of the ALA neuron, and may play a role in ALA axon migration (PubMed:20501595). Involved in development and function of the AIY interneurons, acting by regulating expression of LIM/homeobox protein ttx-3 (PubMed:11493519, PubMed:15177025, PubMed:19386265). Also acts in an autoregulatory feedback loop to maintain its own expression (PubMed:19386265). Modulates lifespan, perhaps acting in the AIY interneurons (PubMed:21055415). Plays a role in fertility and egg- laying behavior (PubMed:21055415). [The UniProt Consortium]