Anti-CD89

0.5mg/ml if reconstituted with 0.2ml sterile DI water. FCAR, Receptor for Fc fragment of IGA, is also known as CD89. It is a glycoprotein of 50-100 kD present on a number of cell types, including neutrophils, monocytes, macrophages, and eosinophils. CD89 interacts with aggregated IgAs (but not IgGs), such as IgA coated on the surface of an invading microorganism, and mediates several immunologic defense processes such as phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Protein function: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. [The UniProt Consortium]