Anti-CD54 (human), Azide Free Clone B-H17 [Mouse]

Specificity: Recognises the Intercellular Adhesion Molecule-1 (ICAM-1), a 75-115 kDa protein, Format: Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free, Working Dilution: The suggested coating concentration range below should be optimised by each laboratory for each application. ELISA: 1-10µg/ml, Storage: Store at +2-8°C for 12 months. For longer storage, freeze aliquots, Application Notes: This Antibody can be used as Capture in a human **** sandwich Immunoassay to detect human **** in combination with biotinylated human **** Detection Antibody (Cat n° ***.***.***). The suggested coating concentration range below should be optimised by each laboratory for each application. Protein function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. [The UniProt Consortium]