Anti-CD42b, gpIb, Biotin conjugated, clone 3H1309

The GPIb/IX complex (CD42a-d) serves as a receptor for von Willebrand Factor (vWF) and thrombin, and mediates adhesion of platelets to subendothelium of damaged vascular walls. The absence of the CD42 complex leads to the Bernard-Soulier Symdrome (BSS). Antibody inhibits the ristocetin-dependent binding of vWF to platelets, ristocetin-induced platelet agglutination, and partially inhibits collagen-induced aggregation. Recommended Secondary Antibody: Streptavidin: RPE, Recommended Negative Controls: Mouse IgG1 Negative Control , Applications:, Flow Cytometry: Neat, Optimal working dilutions to be determined by researcher., , Flow Cytometry: Use 10ul of the suggested working dilution to label 100ul whole blood.