Anti-CD106 (human), Azide Free Clone B-S6 [Mouse]

Specificity: Recognises the Vascular Cellular Adhesion Molecule-1 (VCAM-1), a 110 kDa protein, Format: Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free, Working Dilution: The suggested coating concentration range below should be optimised by each laboratory for each application. ELISA: 0.50-2.5µg/ml, Storage: Store at +2-8°C for 12 months. For longer storage, freeze aliquots, Application Notes: This Antibody can be used as Capture in a human **** sandwich Immunoassay to detect human **** in combination with biotinylated human **** Detection Antibody (Cat n° ***.***.***). The suggested coating concentration range below should be optimised by each laboratory for each application. Protein function: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha- 4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. [The UniProt Consortium]