Anti-Caspase-8 (FLICE, MACH, Mch5), clone 6D221

Caspase-8 (FLICE, MACH, Mch5) is a member of the ICE/CED-3 family of cysteine proteases. It contains two death domains and interacts with FADD (MORT1) and the Fas Ligand induced Death Inducing Surface Complex' (DISC). This complex is involved in the signal transduction that initiates the apoptotic protease cascade in many cell lines. Applications: Suitable for use in Immunocytochemistry, Immunoprecipitation and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml, Optimal dilution to be determined by researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.