Anti-Cas9, clone 3F9

Anti-Cas9, clone 3F9
Aktion:

Gratis WB-Box zu jeder Arigo-Bestellung. 

*1
*1 Angebot gültig bis zum 30.04.2019
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG10706.50 50 µl - -

6 - 14 Werktage

439,00 €
 
Protein function: CRISPR (clustered regularly interspaced short palindromic repeat) is an... mehr
Produktinformationen "Anti-Cas9, clone 3F9"
Protein function: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer, Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity. [The UniProt Consortium]
Schlagworte: Anti-SaCas9, Anti-CRISPR-associated endonuclease Cas9
Hersteller-Nr: ARG10706050

Eigenschaften

Anwendung: WB, ICC, IF, IHC (frozen)
Antikörper-Typ: Monoclonal
Klon: 3F9
Wirt: Mouse
Reaktivität: Bacteria
Immunogen: N-terminal region, aa. 1-608 of Cas9 sequence CDJ55032.1 from S. pyogenes, expressed in and purified from E. coli
Format: Affinity Purified

Datenbank Information

UniProt ID : J7RUA5 | Suche mit UniProt ID

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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