Anti-CARMA1

Anti-CARMA1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with CARMA1 from other sources has not been determined. Protein function: Involved in the costimulatory signal essential for T- cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. [The UniProt Consortium]