Anti-Calreticulin

Anti-Calreticulin Antibody was prepared from monospecific antiserum by delipidation and defibrination. A BLAST analysis was used to suggest cross-reactivity with Calreticulin from Human, mouse, rat, bovine, canine, chicken, guinea pig, monkey, pig, hamster, rabbit , and sheep based on 100% homology with the immunizing sequence. Cross-reactivity with Calreticulin from other sources has not been determined. Cell Signaling research. Protein function: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis. [The UniProt Consortium]