Anti-c-Fos

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-70027.60 60 µl -

7 - 16 Werktage*

158,00 €
E-AB-70027.120 120 µl -

7 - 16 Werktage*

257,00 €
E-AB-70027.200 200 µl -

7 - 16 Werktage*

406,00 €
 
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode... mehr
Produktinformationen "Anti-c-Fos"
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. Protein function: Nuclear phosphoprotein which forms a tight but non- covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD- binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum. [The UniProt Consortium]
Schlagworte: Anti-FOS, Anti-G0S7, Anti-Proto-oncogene c-Fos, Anti-Cellular oncogene fos, Anti-G0/G1 switch regulatory protein 7, c-Fos Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-70027

Eigenschaften

Anwendung: IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse c-FOS

Handhabung & Sicherheit

Lagerung: -20°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-c-Fos"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen