Anti-c-Fos, clone 7D6-A9-D4

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG54149.50 50 µl - -

6 - 14 Werktage*

436,00 €
ARG54149.100 100 µl - -

6 - 14 Werktage*

624,00 €
 
Protein function: Nuclear phosphoprotein which forms a tight but non- covalently linked complex... mehr
Produktinformationen "Anti-c-Fos, clone 7D6-A9-D4"
Protein function: Nuclear phosphoprotein which forms a tight but non- covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD- binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum. [The UniProt Consortium]
Schlagworte: Anti-FOS, Anti-G0S7, Anti-Proto-oncogene c-Fos, Anti-Cellular oncogene fos, Anti-G0/G1 switch regulatory protein 7
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG54149

Eigenschaften

Anwendung: WB
Antikörper-Typ: Monoclonal
Klon: 7D6-A9-D4
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human, monkey, mouse, rat
Immunogen: Purified recombinant human FOS protein fragments expressed in E.coli
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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