Anti-BCAS3

Anti-BCAS3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with BCAS3 from other sources has not been determined. Protein function: Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation. Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin. [The UniProt Consortium]