Anti-BATF3, clone PCRP-BATF3-1E5

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Nucleus. Positive Control: Human tonsil. HeLa or HDLM-2 cells. Chromosome Location: 1q32.3. Protein Function: AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (By similarity). Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes [The Uniprot Consortium]