Anti-Bag3

Bag3 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Mouse and for use in ELISA, IP applications. Bag3 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. Has anti-apoptotic activity. Plays a role in the HSF1 nucleocytoplasmic transport. [The UniProt Consortium]