Anti-ATP1B1 [R02-8B6] Monoclonal Antibody

ATP1B1 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (PubMed:19694409). Plays a role in innate immunity by enhancing virus-triggered induction of interferons (IFNs) and interferon stimulated genes (ISGs). Mechanistically, enhances the ubiquitination of TRAF3 and TRAF6 as well as the phosphorylation of TAK1 and TBK1 (PubMed:34011520) , Involved in cell adhesion and establishing epithelial cell polarity [The Uniprot Consortium]