Anti-ATP11A

Anti-ATP11A Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ATP11A from other sources has not been determined. Protein function: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib. [The UniProt Consortium]