Anti-ATL4

This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Sep 2014], Protein function: Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Secreted, extracellular space, extracellular matrix . Colocalizes with FMN1 microfibrils in the eye ECM.