Anti-ATG16L, CT (ATG16L1, APG16L, Autophagy-related protein 16-1, APG16-like 1)

Anti-ATG16L, CT (ATG16L1, APG16L, Autophagy-related protein 16-1, APG16-like 1)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
032178.200 200 µl - -

3 - 19 Werktage*

728,00 €
 
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic... mehr
Produktinformationen "Anti-ATG16L, CT (ATG16L1, APG16L, Autophagy-related protein 16-1, APG16-like 1)"
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The APG12-APG5-APG16L complex is esential for the elongation of autophagic isolation membranes. This complex initially associates in uniform distribution with small vesicle membranes. During membrane elongation, the complex partitions, with a great concentration building on the outer side of the isolation membrane. Upon completion of the formation of the autophagosome, the APG12-APG5-APG16L dissociates from the membrane. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:50-100, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Hersteller: United States Biological
Hersteller-Nr: 032178

Eigenschaften

Anwendung: ELISA, IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: ATG16L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377~407 amino acids from the C-term of human APG16L.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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