Anti-ATG12

Aktion:

Gratis T-Shirt zu jeder Rockland-Bestellung über 500 €. 

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
600-401-Y76 100 µg - -

1 - 9 Werktage

471,00 €
 
Anti-ATG12 Antibody was affinity purified from monospecific antiserum by immunoaffinity... mehr
Produktinformationen "Anti-ATG12"
Anti-ATG12 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ATG12 from other sources has not been determined. Protein function: Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus. [The UniProt Consortium]
Schlagworte: Anti-ATG12, Anti-APG12, Anti-APG12-like, Anti-Autophagy-related protein 12, Anti-Ubiquitin-like protein ATG12
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 600-401-Y76

Eigenschaften

Anwendung: ELISA, IHC, IF, WB
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: 15 amino acid synthetic peptide from near the internal region of human ATG12.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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