Anti-ATF6

Anti-ATF6 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ATF6 from other sources has not been determined. Protein function: Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. [The UniProt Consortium]