Anti-AST

Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle,it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol,and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids. Protein function: Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids. [The UniProt Consortium]