Anti-ARHGAP18

Anti-ARHGAP18
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ELK-ES1696.50 50 µl - -

10 - 14 Werktage*

173,00 €
ELK-ES1696.100 100 µl - -

10 - 14 Werktage*

290,00 €
 
ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate... mehr
Produktinformationen "Anti-ARHGAP18"
ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al., 2009 [PubMed 19065146]).[supplied by OMIM, Apr 2010], Protein function: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595). [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: Cytoplasm .
Schlagworte: Anti-MacGAP, Anti-Rho GTPase-activating protein 18, Anti-Rho-type GTPase-activating protein 18, ARHGAP18 rabbit pAb
Hersteller: ELK Biotechnology
Hersteller-Nr: ES1696

Eigenschaften

Anwendung: WB, IHC, IF, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, rat, mouse,
Immunogen: The antiserum was produced against synthesized peptide derived from human RHG18. AA range:517-566
MW: 75 kD
Format: Antiserum

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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