Anti-ARFGAP1

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-14599.20 20 µl -

7 - 16 Werktage*

71,00 €
E-AB-14599.60 60 µl -

7 - 16 Werktage*

143,00 €
E-AB-14599.120 120 µl -

7 - 16 Werktage*

238,00 €
E-AB-14599.200 200 µl -

7 - 16 Werktage*

396,00 €
 
The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the... mehr
Produktinformationen "Anti-ARFGAP1"
The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene. Protein function: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine. [The UniProt Consortium]
Schlagworte: Anti-ARF1GAP, Anti-ARFGAP1, Anti-ARF1 GAP, Anti-ARF GAP 1, Anti-ARF1-directed GTPase-activating protein, Anti-ADP-ribosylation factor GTPase-activating protein 1, Anti-ADP-ribosylation factor 1 GTPase-activating protein, ARFGAP1 Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-14599

Eigenschaften

Anwendung: WB, IHC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
Immunogen: Recombinant protein of human ARFGAP1
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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