Anti-APOBEC3C

Anti-APOBEC3C
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R35672-100UG 100 µg - -

3 - 10 Werktage*

755,00 €
 
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... mehr
Produktinformationen "Anti-APOBEC3C"
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C Protein function: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination- independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double- stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV), herpes simplex virus 1 (HHV-1) and Epstein-Barr virus (EBV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. [The UniProt Consortium]
Schlagworte: Anti-A3C, Anti-APOBEC1L, Anti-APOBEC3C, EC=3.5.4.-, Anti-Phorbolin I, Anti-APOBEC1-like, Anti-DNA dC->dU-editing enzyme APOBEC-3C, APOBEC3C Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: R35672

Eigenschaften

Anwendung: WB, ELISA (peptide)
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Goat
Spezies-Reaktivität: human
Immunogen: Amino acids RLLKRRLRESLQ were used as the immunogen for this APOBEC3C antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-APOBEC3C"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen