Anti-ADAM 22 (A Disintegrin And Metalloproteinase 22)

Human ADAM22 is a member of the ADAM (a disintegrin and metalloprotease domain) , family of metalloproteases. Members of this family are membrane-anchored proteins , structurally related to snake venom disintegrins. They have been implicated in a variety of , biological processes involving cell-cell and cell-matrix interactions, such as fertilization, , muscle development, and neurogenesis. ADAM22 is highly expressed in the brain and may , function as an integrin ligand in the brain. The amino acid sequence of human ADAM22 is , 100%, 96% and 92% identical to that of chimpanzee, dog and mouse. Applications: Suitable for use in ELISA, Western Blot, and Immunoprecipitation. Other applications not tested. Recommended Dilution: ELISA: 0.5-1.0ug/ml, Western Blot: 1-2ug/ml, Immunoprecipitation: 25ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.