Anti-ACE2 (human) - Biotin (Clone AC18F)

Anti-ACE2 (human) - Biotin (Clone AC18F)
COVID-19 Forschung
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay30583-50 50 µg -

6 - 10 Werktage*

432,00 €
 
Angiotensin-converting enzyme 2 (ACE2) is a carboxypeptidase and homolog of ACE1 that is encoded... mehr
Produktinformationen "Anti-ACE2 (human) - Biotin (Clone AC18F)"
Angiotensin-converting enzyme 2 (ACE2) is a carboxypeptidase and homolog of ACE1 that is encoded by ACE2 in humans. It is a type I transmembrane protein composed of a cytoplasmic tail and an extracellular domain containing an HEMGH motif, characteristic of zinc-metallopeptidases, which exhibits carboxymonopeptidase activity. ACE2 is expressed in vascular endothelial cells where it catalyzes the conversion of angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to the vasodilatory peptide angiotensin 1-7 to regulate systemic blood pressure. It is also expressed in the epithelial cells of the kidney, heart, lung, small intestine, and liver and has roles in fluid homeostasis, cardiac contractility, and amino acid absorption, as well as the prevention of pulmonary fibrosis and hypertension. ACE2 also acts as a functional receptor for severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 to facilitate viral entry into host cells. Cayman's ACE2 (human) Monoclonal Antibody-Biotinylated (Clone AC18F) can be used for ELISA, flow cytometry (FC), and Western blot (WB) applications.Synonyms: ACE-related Carboxypeptidase, ACEH, Angiotensin-converting Enzyme 2, Angiotensin-converting Enzyme Homolog, Metalloprotease MPROT15. Immunogen: Recombinant human ACE2. Clone Designation: AC18F. Formulation: (Request formulation change), 50 µg of Protein G-purified monoclonal antibody. Storage Buffer: 0.2 µm-filtered solution in PBS, pH 7.4. Host: Mouse. Isotype: IgG1kappa. Applications: ELISA, FC, and WB.
Schlagworte: ACEH, ACE-related Carboxypeptidase, Angiotensin-converting Enzyme Homolog, Metalloprotease MPROT15
Hersteller: Cayman Chemical
Hersteller-Nr: 30583

Eigenschaften

Anwendung: ELISA, FC, WB
Antikörper-Typ: Monoclonal
Klon: AC18F
Konjugat: Biotin
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: Recombinant human ACE2
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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