Zu "K11851" wurden 28 Artikel gefunden!
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Ubiquitin carboxyl-terminal hydrolase 30 (Usp30),...
Artikelnummer: CSB-EP668883MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 57-517aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: TERKKRRKGL VPGLVNLGNT CFMNSLLQGL SACPAFVKWL EEFTTQYSRD QQGPHTHQCL SLTLLNLLKA LSCQEVTEDE VLDASCLLDV LRMYRWQISS FEEQDAHELF HVITSSLEDE RDRQPRVTHL FDVHSLEQQS...
| Schlagworte: | Usp30, Ub-specific protease 30, Ubiquitin thioesterase 30, Deubiquitinating enzyme 30, Ubiquitin carboxyl-terminal... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 59.2 kD |
ab 247,00 €
MF-094
Artikelnummer: TGM-T12024-100mg
Description: MF-094 is a potent and selective inhibitor of USP30 with an IC50 of 120 nM. Target: DUB. Smiles: CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)C3CCCCC3)cccc12. References: Kluge AF, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg...
| Anwendung: | USP30 inhibitor |
| CAS | 2241025-68-1 |
| MW: | 535.7 D |
ab 37,00 €
USP30 inhibitor 11
Artikelnummer: TGM-T13267-100mg
Description: USP30 inhibitor 11 (USP30-IN-11) is a selective USP30 inhibitor (IC50: 0.01 µ?) that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's. Target: DUB. Smiles: COc1ccc(nc1C#N)-c1csc(n1)N(C)C(=O)[C@@H]1CCCN1C#N. References: Mark Kemp, et al. Cyanopyrrolidines as...
| Schlagworte: | USP30-IN-11 |
| Anwendung: | USP30 inhibitor |
| CAS | 2067332-64-1 |
| MW: | 368.41 D |
ab 214,00 €
USP30 inhibitor 18
Artikelnummer: TGM-T36682-100mg
Description: USP30 inhibitor 18 is a selective inhibitor of USP30 (IC50 = 0.02 µM). USP30 inhibitor 18 is able to accelerate mitophagy and increase protein ubiquitination. Target: DUB. Smiles: CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2ccc(F)cc2)cc1. References: Arthur F Kluge, et al. Novel highly...
| Anwendung: | USP30 inhibitor |
| CAS | 2242582-40-5 |
| MW: | 497.58 D |
ab 145,00 €
Anti-USP30
Artikelnummer: CSB-PA004395.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-Ub-specific protease 30, Anti-Ubiquitin thioesterase 30, Anti-Deubiquitinating enzyme 30, Anti-Ubiquitin... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-USP30
Artikelnummer: CSB-PA067099.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-Ub-specific protease 30, Anti-Ubiquitin thioesterase 30, Anti-Deubiquitinating enzyme 30, Anti-Ubiquitin... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
283,00 €
Anti-USP30
Artikelnummer: E-AB-65973.120
USP30, a member of the ubiquitin-specific protease family , is a novel mitochondrial deubiquitinating (DUB) enzyme. Protein function: Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin...
| Schlagworte: | Anti-Ub-specific protease 30, Anti-Ubiquitin thioesterase 30, Anti-Deubiquitinating enzyme 30, Anti-Ubiquitin... |
| Anwendung: | IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 243,00 €
Anti-USP30, clone CL4438
Artikelnummer: ATA-AMAb91295.100
Protein function: Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive...
| Schlagworte: | Anti-Ub-specific protease 30, Anti-Ubiquitin thioesterase 30, Anti-Deubiquitinating enzyme 30, Anti-Ubiquitin... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 320,00 €
Anti-USP30
Artikelnummer: ATA-HPA016952.100
Protein function: Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive...
| Schlagworte: | Anti-Ub-specific protease 30, Anti-Ubiquitin thioesterase 30, Anti-Deubiquitinating enzyme 30, Anti-Ubiquitin... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €
MF094
Artikelnummer: Cay37774-1
MF094 is a ubiquitin-specific protease 30 (USP30) inhibitor (IC50 = 0.12 µM). It is selective for USP30 over 22 other USPs at 10 µM. MF094 (0.6, 1.7, and 5 µM) inhibits ubiquitinylated probe-induced active site modification of USP30 in mitochondria isolated from C2C12 myoblasts. It induces cell death in HSC-4 cells...
| Schlagworte: | alphaS-[(cyclohexylcarbonyl)amino]-N-[5-[[(1,1-dimethylethyl)amino]sulfonyl]-1-naphthalenyl]-benzenepropanamide |
| Anwendung: | USP30 inhibitor |
| CAS | 2241025-68-1 |
| MW: | 535.7 D |
ab 55,00 €
Anti-usp30
Artikelnummer: CSB-PA025721XA01DIL.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-usp30, EC=3.4.19.12, Anti-Ub-specific protease 30, Anti-Ubiquitin thioesterase 30, Anti-Deubiquitinating enzyme 30,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Danio rerio (Zebrafish) (Brachydanio rerio) |
ab 1.529,00 €
Anti-Usp30
Artikelnummer: CSB-PA203951XA01DLU.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-dUSP30, EC=3.4.19.12, Anti-Ub-specific protease 30 homolog, Anti-Ubiquitin thioesterase 30 homolog,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Drosophila melanogaster (Fruit fly) |
ab 1.529,00 €