Zu "K10127" wurden 27 Artikel gefunden!

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Anti-HdmX/MDM4
Anti-HdmX/MDM4

Artikelnummer: A300-287A

Protein function: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. [The UniProt Consortium]
Schlagworte: Anti-MDMX, Anti-MDM4, Anti-Protein Mdmx, Anti-Protein Mdm4, Anti-Double minute 4 protein, Anti-p53-binding protein Mdm4,...
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-HdmX/MDM4 Recombinant Monoclonal
Anti-HdmX/MDM4 Recombinant Monoclonal

Artikelnummer: A700-000

Protein function: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. [The UniProt Consortium]
Schlagworte: Anti-MDMX, Anti-MDM4, Anti-Protein Mdmx, Anti-Protein Mdm4, Anti-Double minute 4 protein, Anti-p53-binding protein Mdm4,...
Anwendung: WB, IP, FC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 172,00 €
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Anti-MDM4
Anti-MDM4

Artikelnummer: G-CAB1747.100

Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
448,00 €
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Anti-HdmX/MDM4
Anti-HdmX/MDM4

Artikelnummer: A303-870A

Protein function: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. [The UniProt Consortium]
Schlagworte: Anti-MDMX, Anti-MDM4, Anti-Protein Mdmx, Anti-Protein Mdm4, Anti-Double minute 4 protein, Anti-p53-binding protein Mdm4,...
Anwendung: WB, IP
Wirt: Goat
Spezies-Reaktivität: human
ab 164,00 €
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Anti-MDM4 / MDMX
Anti-MDM4 / MDMX

Artikelnummer: NSJ-R31805

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Protein Mdm4 is a protein that in humans is encoded by the MDM4 gene. This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein...
Schlagworte: Anti-MDMX, Anti-MDM4, Anti-Protein Mdmx, Anti-Protein Mdm4, Anti-Double minute 4 protein, Anti-p53-binding protein Mdm4,...
Anwendung: WB, IHC (paraffin)
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
755,00 €
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NSC-207895
NSC-207895

Artikelnummer: LKT-N7209.1

NSC-207895 is a benzofuroxan derivative that inhibits MDMX. NSC-207895 exhibits anticancer activity, increasing Bax, PIG3, and PUMA and inducing apoptosis in breast cancer cells.
Schlagworte: NSC207895
Anwendung: MDMX inhibitor
CAS 58131-57-0
MW: 279.25 D
ab 137,00 €
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SJ 172550
SJ 172550

Artikelnummer: Cay19999-1

SJ 172550 is an inhibitor of MDMX that disrupts MDMX-p53 peptide interaction with an EC50 value of 4.3 µM. It forms a covalent, but reversible, cysteine adduct in the MDMX p53-binding domain, locking MDMX into a conformation that prevents binding to p53. SJ 172550 induces apoptosis, increases p53 target gene...
Schlagworte: MDMX Inhibitor II,...
Anwendung: MDM4 inhibitor
CAS 431979-47-4
MW: 428.9 D
ab 64,00 €
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Anti-MDM4 / MDMX
Anti-MDM4 / MDMX

Artikelnummer: ARG59046.50

Protein function: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. [The UniProt Consortium]
Schlagworte: Anti-MDMX, Anti-MDM4, Anti-Protein Mdm4, Anti-Protein Mdmx, Anti-Double minute 4 protein, Anti-p53-binding protein Mdm4,...
Anwendung: IHC (paraffin), WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
520,00 €
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NSC 207895
NSC 207895

Artikelnummer: Cay27949-1

NSC 207895 is an inhibitor of the p53-binding protein MDMX. It decreases MDMX promoter activity in a reporter assay using HT-1080 cells in a concentration-dependent manner. NSC 207895 (5 µmol/L) decreases the expression and protein levels of MDMX and increases the expression of the p53 target gene CDKN1 (p21) in...
Schlagworte: NSC 179940, XI-006, 4-(4-methyl-1-piperazinyl)-7-nitro-2,1,3-benzoxadiazole, 3-oxide
Anwendung: MDM4 inhibitor
CAS 58131-57-0
MW: 279.3 D
ab 125,00 €
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Anti-MDM4
Anti-MDM4

Artikelnummer: ATA-HPA018919.100

Protein function: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. [The UniProt...
Schlagworte: Anti-MDM4, Anti-MDMX, Anti-Protein Mdmx, Anti-Protein Mdm4, Anti-Double minute 4 protein, Anti-p53-binding protein Mdm4,...
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 300,00 €
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Anti-MDM4
Anti-MDM4

Artikelnummer: ATA-HPA048821.100

Protein function: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. [The UniProt...
Schlagworte: Anti-MDM4, Anti-MDMX, Anti-Protein Mdmx, Anti-Protein Mdm4, Anti-Double minute 4 protein, Anti-p53-binding protein Mdm4,...
Anwendung: ICC, WB
Wirt: Rabbit
Spezies-Reaktivität: human
ab 300,00 €
Bewerten
-10 %
Rabattaktion
Anti-phospho-MDMX (Ser367)
Anti-phospho-MDMX (Ser367)

Artikelnummer: ELK-ES6213.100

This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a...
Schlagworte: Anti-phospho-MDM4, Anti-phospho-MDMX, Anti-phospho-Protein Mdmx, Anti-phospho-Protein Mdm4, Anti-phospho-Double minute 4...
Anwendung: WB, IHC, IF, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
169,00 € ab 152,10 €
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