- Suchergebnis für K08527
Cookie-Einstellungen
Diese Website benutzt Cookies, die für den technischen Betrieb der Website erforderlich sind und stets gesetzt werden. Andere Cookies, die den Komfort bei Benutzung dieser Website erhöhen, der Direktwerbung dienen oder die Interaktion mit anderen Websites und sozialen Netzwerken vereinfachen sollen, werden nur mit Ihrer Zustimmung gesetzt.
Konfiguration
Technisch erforderlich
Diese Cookies sind für die Grundfunktionen des Shops notwendig.
"Alle Cookies ablehnen" Cookie
"Alle Cookies annehmen" Cookie
Ausgewählter Shop
CSRF-Token
Cookie-Einstellungen
FACT-Finder Tracking
Individuelle Preise
Kundenspezifisches Caching
Session
Währungswechsel
Komfortfunktionen
Diese Cookies werden genutzt um das Einkaufserlebnis noch ansprechender zu gestalten, beispielsweise für die Wiedererkennung des Besuchers.
Facebook-Seite in der rechten Blog - Sidebar anzeigen
Merkzettel
Statistik & Tracking
Endgeräteerkennung
Kauf- und Surfverhalten mit Google Tag Manager
Partnerprogramm
Zu "K08527" wurden 74 Artikel gefunden!
Filter schließen
Filtern nach:
Für die Filterung wurden keine Ergebnisse gefunden!
NEU
Artikelnummer: Cay39995-1
YCT529 is an antagonist of retinoic acid receptor alpha (RARalpha, IC50 = 6.8 nM). It is selective for RARalpha over RARbeta and RARgamma (IC50s = >3,700 nM for both). YCT529 (7.5 mg/kg per week) reversibly reduces epidydimal sperm counts without reducing serum testosterone levels in male mice. It reduces germinal...
Schlagworte: | GPHR-00354529, 4-(5-(2,2-dimethyl-4-(p-tolyl)-2H-chromen-6-yl)-1H-pyrrol-2-yl)benzoate, sodium salt |
Anwendung: | RARalpha antagonist |
MW: | 434.5 D |
ab 141,00 €
Artikelnummer: ELK-ELK1978.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human RARa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human RARa. Next,...
Schlagworte: | RARA, NR1B1, RAR-alpha, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay14587-1
9-cis-Retinoic acid is a natural metabolite of vitamin A, derived from the intermediate all-trans retinoic acid (Cay-11017). It potently activates all isoforms of retinoic acid receptor (RAR) (Ki = 0.5-27 nM) as well as retinoid X receptor (RXR) isoforms (Ki = 3.8-12 nM). RAR heterodimerizes with RXR, while RXR can...
Schlagworte: | Alitretinoin, 9-cis RA, NSC 659772, Panretin, 9-cis-retinoic acid |
Anwendung: | RAR and RXR activator |
CAS | 5300-03-8 |
MW: | 300.4 D |
ab 66,00 €
Artikelnummer: Cay16029-1
BMS 195614 is a neutral retinoic acid receptor (RAR) alpha-selective antagonist (Ki = 2.5 nM). It antagonizes agonist-induced coactivator recruitment and moderately decreases SMRT binding to RAR but does not significantly affect nuclear receptor corepressor binding.Formal Name:...
Schlagworte: | BMS 614, 4-[[[5,6-dihydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]-benzoic acid |
Anwendung: | RARA antagonist |
CAS | 182135-66-6 |
MW: | 448.5 D |
ab 39,00 €
Artikelnummer: Cay16144-1
TTNPB is an analog of retinoic acid (Cay-11017) that potently and selectively activates retinoic acid receptors (EC50s = 21, 4, and 2.4 nM for RARalpha, RARbeta, and RARgamma, respectively). It does not act on retinoid X receptors and weakly agonizes farnesoid X receptor (EC50 > 1 µM). TTNPB is used to study RAR...
Schlagworte: | AGN 191183, Arotinoid Acid, Ro 13-7410,... |
Anwendung: | Retinoic acid receptor agonist |
CAS | 71441-28-6 |
MW: | 348.5 D |
ab 60,00 €
Artikelnummer: Cay15261-1
AM580 is a retinoic acid receptor agonist that is selective for RARalpha (Kd = 8 nM, AC50 = 0.36 nM) compared to RARbeta (Kd = 131 nM, AC50 = 24.6 nM) and RARgamma (Kd = 450 nM, AC50 = 27.9 nM). It demonstrates greater specific binding to RARalpha compared to retinoic acid (Cay-11017), which exhibits little...
Schlagworte: | CD336, NSC 608001, Ro 40-6055, 4-[[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbonyl]amino]-benzoic acid |
Anwendung: | RAR alpha (retinoic acid receptor alpha) agonist |
CAS | 102121-60-8 |
MW: | 351.4 D |
ab 43,00 €
Artikelnummer: Cay11017-500
all-trans Retinoic acid is a metabolite of vitamin A and a ligand for retinoic acid receptors (RARs) with IC50 values of 9, 3, and 10 nM for RARalpha, RARbeta, and RARgamma, respectively, in radioligand binding assays. It induces expression of a luciferase reporter in COS-7 cells expressing RARalpha, RARbeta, or...
Schlagworte: | atRA, NSC 122578, NSC 122758, RA, Vitamin A Acid,... |
Anwendung: | RAR / RXR ligand |
CAS | 302-79-4 |
MW: | 300.4 D |
ab 48,00 €
Artikelnummer: BPS-60503
2x10(6) cells. The RARalpha Reporter (Luc)-HEK293 Cell Line is designed for monitoring the activity of retinoic acid receptor alpha (RARalpha). The RARalpha Reporter (Luc)-HEK293 Cell Line contains a firefly luciferase gene under the control of retinoic acid response elements stably integrated into HEK293 cells...
Schlagworte: | RARA, NR1B1, RAR-alpha, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1, |
Anwendung: | RARalpha reporter assays |
Wirt: | Human cells |
Spezies-Reaktivität: | human |
3.193,00 €
Artikelnummer: IB-IB02201
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoic acid receptor, alpha (NR1B1), a ligand-dependent transcription factor commonly referred to as RARA or RARalpha. INDIGO's reporter cells include the luciferase...
Schlagworte: | RARA, NR1B1, RAR-alpha, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1 |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
ab 1.448,00 €
Artikelnummer: Cay25415-1
all-trans Retinoic acid-d5 is intended for use as an internal standard for the quantification of all-trans retinoic acid (Cay-11017) by GC- or LC-MS. all-trans Retinoic acid is a metabolite of vitamin A and a ligand for retinoic acid receptors (RARs) with IC50 values of 9, 3, and 10 nM for RARalpha, RARbeta, and...
Schlagworte: | atRA-d5, RA-d5, Vitamin A Acid-d5,... |
Anwendung: | RAR / RXR ligand, protein synthesis inhibitor, GC-MS, LC-MS, internal standard |
MW: | 305.5 D |
ab 287,00 €
Artikelnummer: Cay34388-10
4-oxo Isotretinoin is an active metabolite of the retinoid isotretinoin (Cay-21648). It is formed from isotretinoin by several cytochrome P450 (CYP450) isoforms, including CYP3A, CYP2B6, and CYP2C19. 4-oxo Isotretinoin (10 µM) increases protein expression of cytokeratin 7 (CK7) and CK19 in normal human epidermal...
Schlagworte: | Ro 22-6595, 13-cis-4-oxo-retinoic acid |
Anwendung: | Active isotretinoin metabolite |
CAS | 71748-58-8 |
MW: | 314.4 D |
ab 48,00 €
Artikelnummer: Cay18658-5
Ch 55 is a synthetic analog of retinoic acid (Cay-11017) that binds to retinoic acid receptors with similar efficiency as retinoic acid (Kis in the nM range) yet does not display affinity for cellular retinoic acid-binding protein (Ki = 540 µM). Ch 55 has been shown to inhibit squamous cell differentiation of rabbit...
Schlagworte: | 4-[(1E)-3-[3,5-bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propen-1-yl]-benzoic acid |
Anwendung: | Retinoic acid receptor ligand |
CAS | 110368-33-7 |
MW: | 364.5 D |
ab 50,00 €