Zu "K07294" wurden 160 Artikel gefunden!
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Anti-Recombinant PPARalpha, clone 9C5
Artikelnummer: E-AN300914L.100
Peroxisome proliferator activated receptor alpha(PPARA) Homo sapiens Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in...
| Schlagworte: | Anti-PPARA, Anti-Nuclear receptor subfamily 1 group C member 1, Anti-Peroxisome proliferator-activated receptor alpha,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
GW 6471
Artikelnummer: Cay11697-1
The peroxisome proliferator-activated receptor alpha (PPARalpha) is a nuclear receptor that regulates the expression of genes involved in fatty acid metabolism, lipoprotein synthesis and metabolism, and inflammation. GW 6471 is an antagonist of PPARalpha (IC50 = 240 nM). It drives the displacement of coactivators...
| Schlagworte: | N-[(2S)-2-[[(1Z)-1-methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propen-1-yl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)e... |
| Anwendung: | PPARalpha antagonist |
| CAS | 880635-03-0 |
| MW: | 619.7 D |
ab 69,00 €
Wy 14643
Artikelnummer: Cay70730-10
Wy 14643 is an agonist of peroxisome proliferator-activated receptor alpha (PPARalpha). It selectively transactivates PPARalpha over PPARgamma in a reporter assay using CV-1 mouse fibroblasts when used at a concentration of 100 µM. Wy 14643 (2 mg/kg) decreases distal colon protein levels of IFN-gamma, TNF-alpha,...
| Schlagworte: | Pirinixic Acid, [[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-acetic acid |
| Anwendung: | PPAR activator |
| CAS | 50892-23-4 |
| MW: | 323.8 D |
ab 26,00 €
PPARalpha Transcription Factor Assay Kit
Artikelnummer: Cay10006915-96
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the large family of nuclear hormone receptors. There are three subtypes, PPARalpha, beta/delta, and gamma, which are expressed at variable levels in different tissues. The Cayman Chemical PPARalpha...
| Schlagworte: | Peroxisome Proliferator-activated Receptor alpha Transcription Factor Assay Kit |
| Anwendung: | PPAR binding detection |
| Spezies-Reaktivität: | human |
755,00 €
GW 7647
Artikelnummer: Cay10008613-1
Peroxisome proliferator-activated receptor-alpha (PPARalpha) is a ligand-activated transcription factor involved in the regulation of lipid homeostasis. Activation of PPARalpha results in expression of a variety of genes, particularly those involved in fatty acid beta-oxidation, binding, and transport. GW 7647 is a...
| Schlagworte: | 2-methyl-2-[[4-[2-[[(cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-propanoic acid |
| Anwendung: | PPARalpha agonist |
| CAS | 265129-71-3 |
| MW: | 502.8 D |
ab 58,00 €
PPARalpha (human) Reporter Assay Kit
Artikelnummer: IB-IB00111
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or PPARalpha. INDIGO's reporter cells include...
| Schlagworte: | NR1C1, PPARA, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, Peroxisome proliferator-activated receptor alpha |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
Lanifibranor
Artikelnummer: Cay25572-25
Lanifibranor is an agonist of peroxisome proliferator-activated receptors (PPARs) with EC50 values of 1,537, 866, and 206 nM for human recombinant PPARalpha, PPARbeta, and PPARgamma, respectively, for transactivation activity. It increases beta-oxidation in Huh-7 and C2C12 cells when used at concentrations of 1 and...
| Schlagworte: | IVA337, 1-(6-benzothiazolylsulfonyl)-5-chloro-1H-indole-2-butanoic acid |
| Anwendung: | PPAR agonist |
| CAS | 927961-18-0 |
| MW: | 434.9 D |
ab 126,00 €
Anti-PPARalpha
Artikelnummer: Cay101710-1
Peroxisome proliferator-activated receptor alpha (PPARalpha) is a member of the nuclear receptor family of ligand-activated transcription factors that regulates a variety of metabolic functions and inflammation. It contains an N-terminal domain that is subject to phosphorylation, a DNA-binding domain, and a...
| Schlagworte: | Anti-PPARA, Anti-NR1C1, Anti-PPAR-alpha, Anti-PPAR-alpha, Anti-Nuclear receptor subfamily 1 group C member 1, Anti-Nuclear... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
Fenofibric Acid
Artikelnummer: Cay19262-500
Fenofibric acid is an agonist of peroxisome proliferator-activated receptor alpha (PPARalpha), PPARgamma, and PPARdelta (EC50s = 22.4, 1.47, and 1.06 µM, respectively, in a transactivation assay) and an active metabolite of the PPARalpha agonist fenofibrate (Cay-10005368). It is formed by the hydrolysis of...
| Schlagworte: | FNF Acid, NSC 281318, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid |
| Anwendung: | PPAR alpha agonist, antihyperlipidemic |
| CAS | 42017-89-0 |
| MW: | 318.8 D |
ab 51,00 €
9,10-Dihydroxystearic Acid
Artikelnummer: Cay28612-1
9,10-Dihydroxystearic acid is an oxidation product of oleic acid (Cay-90260, Cay-24659) that can be formed from oleic acid in HepG2 cells. It activates peroxisome proliferator-activated receptor alpha (PPARalpha) in CV-1 cells when used at concentrations ranging from 50 to 100 µM. 9,10-Dihydroxystearic acid (4% in...
| Schlagworte: | NSC 60305, 9,10-dihydroxy-octadecanoic acid |
| Anwendung: | Oleic acid oxidation product, PPARalpha activator |
| CAS | 120-87-6 |
| MW: | 316.5 D |
ab 69,00 €
Tesaglitazar
Artikelnummer: Cay16791-50
Peroxisome proliferator-activated receptors (PPARs) are activated by fatty acids and eicosanoids as well as antidyslipidemic agents. Among the receptor isotypes, PPARalpha demonstrates a particular role in fatty acid oxidation whereas PPARgamma is known to be involved in adipocyte differentiation and lipid storage....
| Schlagworte: | AZ 242, GalidaTM, (alphaS)-ethoxy-4-[2-[4-[(methylsulfonyl)oxy]phenyl]ethoxy]-benzenepropanoic acid |
| Anwendung: | PPARgamma / alpha agonist |
| CAS | 251565-85-2 |
| MW: | 408.5 D |
ab 58,00 €
![3-Aminoisobutyric acid [BAIBA]](https://www.biomol.com/media/image/b0/d9/b8/AG-CR1-3596-G001_200x200.png "3-Aminoisobutyric acid [BAIBA]")
3-Aminoisobutyric acid [BAIBA]
Artikelnummer: AG-CR1-3596-M250
White solid. Soluble in DMSO or water. Catabolite of thymine, Small molecule myokine. Browning inducer of white adipose tissue (WAT) into brown adipose tissue (BAT), PGC-1alpha-mediated and exercise-triggered nonadrenergic activator of the thermogenic program in WAT. Increases the expression of brown...
| Schlagworte: | beta-Aminoisobutyric acid, BAIBA, 3-Amino-2-methylpropanoic acid, DL-3-Aminoisobutyric acid, alpha-Methyl-beta-alanine,... |
| Anwendung: | Small molecule myokine |
| CAS | 144-90-1 |
| MW: | 103,1 D |
ab 55,00 €