Zu "K05692" wurden 161 Artikel gefunden!
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Latrunculin A
Artikelnummer: Cay10010630-100
Actin disruption is used to study cell functions in vitro (e.g., migration, endocytosis) and in vivo (e.g., tumor cell invasion). Latrunculin A is a bioactive 2-thiazolidinone macrolide derived from sponges that sequesters G-actin and prevents F-actin assembly. It binds monomeric actin with 1:1 stoichiometry and can...
| Schlagworte: | NSC 613011,... |
| Anwendung: | Actin polymerization inhibitor |
| CAS | 76343-93-6 |
| MW: | 421.6 D |
ab 66,00 €
Cytochalasin D
Artikelnummer: Cay11330-1
The cytochalasins are cell-permeable fungal metabolites that inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin D is a cell-permeable inhibitor that binds actin filaments, but not actin monomers, to inhibit...
| Schlagworte: | NSC 209835,... |
| Anwendung: | Cell-permeable actin polymerization inhibitor |
| CAS | 22144-77-0 |
| MW: | 507.6 D |
ab 83,00 €
Cytochalasin B
Artikelnummer: Cay11328-10
Cytochalasin B is a cell-permeable mycotoxin which binds to the barbed end of actin, reversibly inhibiting the elongation and shortening of actin filaments. By disrupting actin polymerization, cytochalasin B blocks diverse cellular functions, including cell division, migration, phagocytosis, exocytosis, chemotaxis,...
| Schlagworte: | NSC 107658, Phomin,... |
| Anwendung: | Mycotoxin |
| CAS | 14930-96-2 |
| MW: | 479.6 D |
ab 60,00 €
Latrunculin B
Artikelnummer: AG-CN2-0031-M001
Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be...
| Schlagworte: | LAT-B, NSC 339663 |
| Anwendung: | Actin polymerization inhibitor |
| CAS | 76343-94-7 |
| MW: | 395,5 D |
ab 143,00 €
Pig ACTb (Actin Beta) ELISA Kit
Artikelnummer: ELK-ELK8480.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Pig ACTb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Pig ACTb. Next,...
| Schlagworte: | ACTB |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | swine |
ab 303,00 €
Human ACTb (Actin Beta) ELISA Kit
Artikelnummer: ELK-ELK4924.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ACTb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ACTb. Next,...
| Schlagworte: | ACTB |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 303,00 €
Anti-beta-actin
Artikelnummer: ELK-EA014.50
beta-Actin is one of six different actin isoforms that have been identified. The actin molecules found in cells of various species and tissues tend to be very similar in their immunological and physical properties. Therefore, Antibodies against beta-Actin are useful as loading controls for Western Blotting. However...
| Schlagworte: | Anti-ACTB, beta-actin Rabbit pAb |
| Anwendung: | WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
169,00 €
Latrunculin A
Artikelnummer: AG-CN2-0027-C100
Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Potent phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in...
| Schlagworte: | LAT-A, NSC 613011 |
| Anwendung: | Actin polymerization inhibitor |
| CAS | 76343-93-6 |
| MW: | 421,6 D |
ab 138,00 €
Phalloidin Amine
Artikelnummer: ABD-5302
Phalloidin, a bicyclic heptapeptide toxin, binds specifically at the interface between F-actin subunits, locking adjacent subunits together. Phalloidin binds to actin filaments much more tightly than to actin monomers, leading to a decrease in the rate constant for the dissociation of actin subunits from filament...
| Anwendung: | Actin filament stabilizer, ATP hydrolysis activity inhibitor |
| CAS | 87876-22-0 |
| MW: | 901,91 D |
279,00 €
Anti-beta-Actin
Artikelnummer: 600-401-886
Protein function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. [The UniProt Consortium]
| Schlagworte: | Anti-ACTB |
| Anwendung: | ELISA, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
546,00 €
Jasplakinolide
Artikelnummer: Cay11705-100
Jasplakinolide is a natural macrocyclic peptide first isolated from a marine sponge. It potently inhibits the proliferation of PC3 prostate carcinoma cells (IC50 = 35 nM) by binding F-actin (KD = 15 nM). This binding of jasplakinolide to actin, which is competitive with phalloidin, stabilizes actin filaments in...
| Schlagworte: | NSC 613009,... |
| Anwendung: | Actin studies |
| CAS | 102396-24-7 |
| MW: | 709.7 D |
ab 214,00 €
ACTB, Human actin, beta, Real Time PCR Primer Set
Artikelnummer: VHPS-110
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | ACTB, Beta-actin, Actin, cytoplasmic 1, Actin, cytoplasmic 1, N-terminally processed |
| Anwendung: | RNA quantification |
43,00 €