- Suchergebnis für K04362
Cookie-Einstellungen
Diese Website benutzt Cookies, die für den technischen Betrieb der Website erforderlich sind und stets gesetzt werden. Andere Cookies, die den Komfort bei Benutzung dieser Website erhöhen, der Direktwerbung dienen oder die Interaktion mit anderen Websites und sozialen Netzwerken vereinfachen sollen, werden nur mit Ihrer Zustimmung gesetzt.
Konfiguration
Technisch erforderlich
Diese Cookies sind für die Grundfunktionen des Shops notwendig.
"Alle Cookies ablehnen" Cookie
"Alle Cookies annehmen" Cookie
Ausgewählter Shop
CSRF-Token
Cookie-Einstellungen
FACT-Finder Tracking
Individuelle Preise
Kundenspezifisches Caching
Session
Währungswechsel
Komfortfunktionen
Diese Cookies werden genutzt um das Einkaufserlebnis noch ansprechender zu gestalten, beispielsweise für die Wiedererkennung des Besuchers.
Facebook-Seite in der rechten Blog - Sidebar anzeigen
Merkzettel
Statistik & Tracking
Endgeräteerkennung
Kauf- und Surfverhalten mit Google Tag Manager
Partnerprogramm
Zu "K04362" wurden 189 Artikel gefunden!
Filter schließen
Filtern nach:
Für die Filterung wurden keine Ergebnisse gefunden!
Artikelnummer: BPS-40210
Active recombinant human FGFR1 (399-822) was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. The gene accession number is NM_023110. Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Schlagworte: | N-sam, CD331, BFGFR, FLT-2, FGFR1, FGFR-1, bFGF-R-1, Proto-oncogene c-Fgr, Fms-like tyrosine kinase 2, Fibroblast growth... |
Anwendung: | Enzyme kinetics, inhibitor screening |
MW: | 73 kD |
862,00 €
Artikelnummer: Cay39292-1
BGJ398 is an orally available inhibitor of human FGFRs (IC50s = 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively). It inhibits FGFR4 and VEGFR2 with IC50 values of 60 and 180 nM, respectively, and displays comparatively little activity towards Abl, Fyn, Kit, Lck, Lyn, and Yes (IC50s = 0.3-2.5 µM). BGJ398...
Schlagworte: | Infigratinib (phosphate), NVP-BGJ398 (phosphate),... |
Anwendung: | Pan FGFR inhibitor |
CAS | 1310746-10-1 |
MW: | 658.5 D |
ab 34,00 €
Artikelnummer: ELK-ELK2848.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human FGFR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human FGFR1. Next,...
Schlagworte: | N-sam, CD331, BFGFR, FLT-2, FGFR1, FGFR-1, bFGF-R-1, Proto-oncogene c-Fgr, Fms-like tyrosine kinase 2, Fibroblast growth... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-ELK6840.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat FGFR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat FGFR1. Next,...
Schlagworte: | MFR, Flg, CD331, Fgfr1, FGFR-1, bFGF-R-1, Proto-oncogene c-Fgr, Fibroblast growth factor receptor 1, Basic fibroblast... |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
ab 365,00 €
Artikelnummer: ELK-ELK2883.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse FGFR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse FGFR1. Next,...
Schlagworte: | MFR, Flg, CD331, Fgfr1, FGFR-1, bFGF-R-1, Proto-oncogene c-Fgr, Fibroblast growth factor receptor 1, Basic fibroblast... |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: BPS-101820-1
Recombinant human FGFR3 (fibroblast growth factor receptor 3, also known as CD333), encompassing amino acids 23-375 corresponding to the extracellular portion of the receptor. This construct contains a C-terminal Fc domain followed by an Avi-Tag(TM). This protein has a Factor Xa cleavage site prior to the Fc domain....
Schlagworte: | N-sam, CD331, BFGFR, FLT-2, FGFR1, FGFR-1, bFGF-R-1, Proto-oncogene c-Fgr, Fms-like tyrosine kinase 2, Fibroblast growth... |
Anwendung: | Cancer therapy target, biotin-avidin-pulldown |
Exprimiert in: | Human cells |
Ursprungsart: | human |
MW: | 67+glyc kD |
ab 525,00 €
Artikelnummer: Cay17120-1
CH5183284 is a potent, selective inhibitor of the kinase activity of fibroblast growth factor receptors (FGFRs) 1, 2, and 3 (IC50s = 9.3, 7.6, and 22 nM, respectively). It less potently inhibits FGFR4 and platelet-derived growth factor receptor beta (IC50s = 290 and 560 nM, respectively) and displays IC50 values...
Schlagworte: | Debio 1347, [5-amino-1-(2-methyl-1H-benzimidazol-6-yl)-1H-pyrazol-4-yl]-1H-indol-2-yl-methanone |
Anwendung: | FGFR1/2/3 inhibitor |
CAS | 1265229-25-1 |
MW: | 356.4 D |
ab 66,00 €
Artikelnummer: Cay13182-10
SU 5402 is an inhibitor of the tyrosine kinase domains of VEGFR2, FGFR1, and PDGFRbeta (IC50s = 0.02, 0.03, and 0.51 µM, respectively). It is much less effective against other receptor tyrosine kinases. SU 5402 is commonly used to evaluate the role of FGFR1 in cellular functions.Formal Name:...
Schlagworte: | 2-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid |
Anwendung: | FGFR1 /?VEGFR2 inhibitor |
CAS | 215543-92-3 |
MW: | 296.3 D |
ab 32,00 €
Artikelnummer: Cay21136-1
TAS 120 is an orally bioavailable inhibitor of fibroblast growth factor receptors (FGFRs) that irreversibly inhibits all four FGFR subtypes at nanomolar concentrations. It prevents phosphorylation of FGFRs and impedes downstream signaling pathways in cells. TAS 120 blocks the proliferation of human cancer cell lines...
Schlagworte: | 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-pyrrolidinyl]-2-propen-1-one |
Anwendung: | FGFR inhibitor |
CAS | 1448169-71-8 |
MW: | 418.5 D |
ab 77,00 €
Artikelnummer: Cay33260-5
Pemigatinib is an inhibitor of FGFR (IC50s = 0.4, 0.5, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively). It is selective for FGFR1, FGFR2, and FGFR3 over FGFR4 and the kinase insert domain receptor (KDR, IC50s = 30 and 70 nM, respectively), as well as over a panel of 56 tyrosine and serine/threonine kinases at 10...
Schlagworte: | INCB054828,... |
Anwendung: | FGFR inhibitor |
CAS | 1513857-77-6 |
MW: | 487.5 D |
ab 65,00 €
Artikelnummer: Cay19375-1
Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRalpha, PDGFRbeta and Kit (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces...
Schlagworte: | E-7080, ER-203492-00, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide |
Anwendung: | VEGFR / FGFR / PDGFR inhibitor |
CAS | 417716-92-8 |
MW: | 426.9 D |
ab 43,00 €
Artikelnummer: Cay22464-5
PD 166866 is a potent inhibitor of fibroblast growth factor receptor 1 (FGFR1, IC50 = 52.4 nM, Ki = 45.2 nM). It is selective for FGFR1 over PDGFR, EGFR, C-SRC, MEK, PKC, insulin receptor tyrosine kinase, and CDK4 (IC50s = >50 µM). PD 166866 inhibits FGFR1 autophosphorylation in NIH3T3 and L6 cells (IC50s = 10.8 and...
Schlagworte: | N-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-urea |
Anwendung: | FGFR1 inhibitor |
CAS | 192705-79-6 |
MW: | 396.4 D |
ab 43,00 €