Zu "K04152" wurden 42 Artikel gefunden!
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CHO-K1/H4/Galpha15 Stable Cell Line
Artikelnummer: GSC-M00289
Recombinant CHO-K1 cells stably overexpress human histamine receptor H4 (H4) on the surface and contain high levels of G protein Galphai to couple with the receptor in downstream signaling pathways.
| Schlagworte: | HRH4, GPRv53, AXOR35, SP9144, Pfi-013, Histamine H4 receptor, G-protein coupled receptor 105 |
11.424,00 €
Adriforant (hydrochloride hydrate)
Artikelnummer: Cay43638-1
A histamine H4 receptor antagonist (Ki = 6.17 nM), prevents histamine-induced shape change, CD11b protein upregulation, and actin polymerization in isolated human eosinophils (IC50s = 0.65, 4.9, and 1.3 nM, respectively), inhibits histamine-induced calcium influx in primary mouse dorsal root ganglion neurons at 10...
| Schlagworte: | PF-3893787, ZPL-389, N4-(cyclopropylmethyl)-6-[(3R)-3-(methylamino)-1-pyrrolidinyl]-2,4-pyrimidinediamine, dihydrochloride... |
| Anwendung: | Histamine H4 receptor antagonist |
| CAS | 2096455-90-0 |
| MW: | 335.3 D |
ab 53,00 €
JNJ-7777120
Artikelnummer: Cay10011925-10
JNJ-7777120 is a potent and selective histamine H4 receptor antagonist, with a Ki value of approximately 4 nM against the human, mouse, and rat H4 receptors. Its Ki values for the histamine H1-3 receptors exceed 1 µM, regardless of species, and it has no or negligible effects on a range of other receptors and...
| Schlagworte: | (5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)-methanone |
| Anwendung: | Histamine H4 receptor antagonist |
| CAS | 459168-41-3 |
| MW: | 277.8 D |
ab 30,00 €
VUF10460
Artikelnummer: Cay14665-5
VUF10460 is a histamine H4 receptor agonist (Kis = 5.01 and 14.13 nM for the human and rat receptors, respectively). It is selective for the rat histamine H4 receptor over the rat histamine H3 receptor (Kis = 34.67 and 1,778.28 nM, respectively). VUF10460 (10 mg/kg) potentiates the formation of HCl-induced ulcers in...
| Schlagworte: | 4-(4-methyl-1-piperazinyl)-6-phenyl-2-pyrimidinamine |
| Anwendung: | Histamine H4 receptor agonist |
| CAS | 1028327-66-3 |
| MW: | 269.4 D |
ab 49,00 €
4-Methylhistamine (hydrochloride)
Artikelnummer: Cay23761-1
4-Methylhistamine is a histamine H4 receptor agonist (Ki = 50 nM). It is >100-fold selective for H4 over other histamine receptors. 4-Methylhistamine inhibits CRE-beta-galactosidase activity induced by forskolin (Cay-11018) with an EC50 value of 39.8 nM in SK-N-MC cells transfected with the human H4 receptor. It...
| Schlagworte: | 4-methyl-1H-imidazole-5-ethanamine, dihydrochloride |
| Anwendung: | Histamine H4 receptor agonist |
| CAS | 36376-47-3 |
| MW: | 198.1 D |
ab 49,00 €
Imetit (hydrobromide)
Artikelnummer: Cay29517-5
Imetit is a histamine H3 and H4 receptor agonist (Kis = 0.3 and 2.7 nM, respectively, in radioligand binding assays). It is selective for histamine H3 and H4 receptors over H1 and H2 receptors at concentrations up to 100 µM, as well as the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 240 nM). Imetit reduces...
| Schlagworte: | VUF 8325, carbamimidothioic acid, 2-(1H-imidazol-5-yl)ethyl ester, dihydrobromide |
| Anwendung: | Histamine H3 & H4 receptor agonist |
| CAS | 32385-58-3 |
| MW: | 332.1 D |
ab 110,00 €
VUF8430 (hydrobromide)
Artikelnummer: Cay27682-1
VUF8430 is a histamine H4 receptor agonist (Ki = 31.6 nM). It is selective for histamine H4 over H1 and H3 receptors in radioligand binding assays (Kis = >1 and 1 µM, respectively) and is less active in isolated guinea pig atria, which endogenously expresses high levels of H2 receptors (pD2 = 3.8). VUF8430 inhibits...
| Schlagworte: | carbamimidothioic acid, 2-[(aminoiminomethyl)amino]ethyl ester, dihydrobromide |
| Anwendung: | Histamine H4 receptor agonist |
| CAS | 100130-32-3 |
| MW: | 323.1 D |
ab 56,00 €
Histamine
Artikelnummer: Cay33828-5
Histamine is a biogenic amine. It is produced from histidine in basophils, mast cells, gastric enterochromaffin-like (ECL) cells, and histaminergic neurons by histidine decarboxylase (HDC). Histamine activates the G protein-coupled histamine H1-4 receptors to regulate allergic and inflammatory responses, gastric...
| Schlagworte: | NSC 33792, 1H-imidazole-5-ethanamine |
| Anwendung: | Biogenic amine, histamine H1-4 receptor agonist |
| CAS | 51-45-6 |
| MW: | 111.1 D |
ab 108,00 €
A-943931 (hydrochloride hydrate)
Artikelnummer: Cay34554-1
A-943931 is a histamine H4 receptor antagonist (Ki = 3.8 nM). In vivo, A-943931 inhibits scratching induced by clobenpropit (Cay-10011126) in mice (ED50 = 26 µmoles/kg, i.p.).Formal Name: 4-[(3R)-3-amino-1-pyrrolidinyl]-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-amine, dihydrochloride, hydrate. Molecular...
| Schlagworte: | 4-[(3R)-3-amino-1-pyrrolidinyl]-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-amine, dihydrochloride, hydrate |
| Anwendung: | Histamine H4 receptor antagonist |
| MW: | 368.3 D |
ab 49,00 €
Mouse HRH4 (Histamine Receptor H4) ELISA Kit
Artikelnummer: ELK-ELK6270.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse HRH4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse HRH4. Next,...
| Schlagworte: | H4R, Hrh4, HH4R, Histamine H4 receptor |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 374,00 €
Human HRH4 (Histamine Receptor H4) ELISA Kit
Artikelnummer: ELK-ELK3469.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HRH4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HRH4. Next,...
| Schlagworte: | H4R, HRH4, HH4R, AXOR35, GPRv53, SP9144, Pfi-013, GPCR105, Histamine H4 receptor, G-protein coupled receptor 105 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Rat HRH4 (Histamine Receptor H4) ELISA Kit
Artikelnummer: ELK-ELK7163.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat HRH4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat HRH4. Next,...
| Schlagworte: | H4R, Hrh4, HH4R, Histamine H4 receptor |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 374,00 €