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JFD00244
Artikelnummer: TGM-T15610-10mg
Description: JFD00244 is an inhibitor of sirtuin 2 (SIRT2). It has an anti-tumor effect. Target: Others. Smiles: Oc1ccc(CCNc2ccc(NCCc3ccc(O)cc3)c3C(=O)c4ccccc4C(=O)c23)cc1. References: Ciarlo C, A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development....
| Anwendung: | SIRT2 inhibitor |
| CAS | 96969-83-4 |
| MW: | 478.54 D |
ab 77,00 €
JFD00244
Artikelnummer: Cay14648-10
Human sirtuin 2 (SIRT2) is a NAD+-dependent protein deacetylase with diverse targets, including alpha-tubulin, phosphoenolpyruvate carboxykinase, and forkhead box protein O1. JFD00244 is an inhibitor of SIRT2 (IC50= 56.7 µM). At 5 µM, JFD00244 induces granulocytic differentiation in the acute promyelocytic leukemia...
| Schlagworte: | BML-266, 1,4-bis[[2-(4-hydroxyphenyl)ethyl]amino]-9,10-anthracenedione |
| Anwendung: | SIRT2 inhibitor |
| CAS | 96969-83-4 |
| MW: | 478.5 D |
ab 44,00 €
