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Pictilisib
Artikelnummer: TGM-T1994-100mg
Description: Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110alpha/beta/delta/gamma). Target: Apoptosis, Autophagy, PI3K. Smiles: CS(=O)(=O)N1CCN(Cc2cc3nc(nc(N4CCOCC4)c3s2)-c2cccc3[nH]ncc23)CC1. References: Folkes AJ, et al. The...
| Schlagworte: | GDC-0941, RG7321 |
| CAS | 957054-30-7 |
| MW: | 513.64 D |
ab 40,00 €
GDC-0941
Artikelnummer: Cay11600-10
The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. GDC-0941 is a potent pan inhibitor of class I catalytic subunits of PI3K, inhibiting p110alpha, beta, delta, and gamma with IC50 values of 3, 33, 3, and 75 nM, respectively. It is much less...
| Schlagworte: | GNE-0941, Pictilisib, Pictrelisib,... |
| Anwendung: | PI3K inhibitor |
| CAS | 957054-30-7 |
| MW: | 513.6 D |
ab 183,00 €
GDC-0941
Artikelnummer: LKT-G124082.5
pan-PI3K inhibitor.
| Schlagworte: | GNE-0941, Pictilisib, Pictrelisib, RG7321 |
| Anwendung: | Class I selective PI3K Inhibitor |
| CAS | 957054-30-7 |
| MW: | 513.64 D |
ab 113,00 €
GDC-0941
Artikelnummer: SYN-1041-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. GDC-0941 is a potent class I PI3 kinase (PI3K) inhibitor. It selectively binds to PI3K isoforms in an ATP-competitive manner. It has an IC(50) of 3nM, and shows slight selectivity toward p110beta (11-fold) and p110gamma (25-fold). Target: PI3K , Kinase Group:...
| Schlagworte: | GDC0941 |
| Anwendung: | PI3K inhibitor |
| CAS | 957054-30-7 |
| MW: | 513,6 D |
ab 123,00 €
