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CCT129202
Artikelnummer: TGM-T6435-100mg
Description: CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 µM, 0.198 µM and 0.227 µM, respectively. It is less potent to FGFR3, GSK3beta, PDGFRbeta, etc. Target: Aurora Kinase. Smiles: CN(C)c1ccc(cc1)-c1nc2c(N3CCN(CC(=O)Nc4nccs4)CC3)c(Cl)cnc2[nH]1....
| Anwendung: | Aurora kinase inhibitor |
| CAS | 942947-93-5 |
| MW: | 497.02 D |
ab 40,00 €
CCT129202
Artikelnummer: Cay29053-1
CCT129202 is an Aurora kinase inhibitor that inhibits Aurora A and B by 82 and 60%, respectively, when used at a concentration of 1 µM in cell-free assays. It is selective for Aurora A and B over a panel of 13 kinases at 1 µM. CCT129202 inhibits growth of COLO 205, SW620, HCT116, HT-29, KW12, HeLa, A2780, OVCAR-8,...
| Schlagworte: | 4-[6-chloro-2-[4-(dimethylamino)phenyl]-3H-imidazo[4,5-b]pyridin-7-yl]-N-2-thiazolyl-1-piperazineacetamide |
| Anwendung: | Aurora kinase inhibitor |
| CAS | 942947-93-5 |
| MW: | 497 D |
ab 69,00 €
