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DTHIB
DTHIB

Artikelnummer: TGM-T8858-100mg

Description: DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation. Target: HSP. Smiles: [O-][N+](=O)c1cc(NC(=O)Nc2ccc(F)cc2)ccc1Cl. References: Dong B , Jaeger A M , Hughes P F , et al. Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock...
Anwendung: Hsf1 inhibitor
CAS 897326-30-6
MW: 309.68 D
ab 31,00 €
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DTHIB
DTHIB

Artikelnummer: Cay37433-100

DTHIB is an inhibitor of heat shock factor 1 (Hsf1). It binds to the DNA-binding domain of Hsf1 (Kd = 160 nM) and inhibits heat-induced increases in the Hsf1 target proteins heat shock protein 27 (Hsp27) and Hsp70 levels in mouse embryonic fibroblasts (MEFs) when used at a concentration of 10 µM. It decreases...
Schlagworte: Direct Targeted Heat Shock Factor 1 Inhibitor, Direct Targeted Hsf1 Inhibitor,...
Anwendung: Hsf1 inhibitor
CAS 897326-30-6
MW: 309.7 D
ab 209,00 €
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