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UoS 12258
Artikelnummer: TGM-T36809-10mg
Description: Positive allosteric modulator of AMPA receptors (pEC50 = 5.2 for potentiation of AMPA-mediated currents in vitro). Also potentiates AMPA-mediated synaptic responses in vivo. Improves performance of rats in various learning and memory paradigms. Target: Others. Smiles:...
| Anwendung: | AMPA receptors positive allosteric modulator |
| CAS | 875927-64-3 |
| MW: | 334.41 D |
ab 280,00 €
UoS 12258
Artikelnummer: Cay36571-10
UoS 12258 is a positive allosteric modulator of AMPA receptors. It potentiates glutamate-induced currents in HEK293 cells expressing human ionotropic glutamate receptor 2 (GluR2) homomeric AMPA receptors (EC50 = 2.51 µM), as well as HEK293 cells expressing GluR1, GluR3, or GluR4 homomeric AMPA receptors. UoS 12258...
| Schlagworte: | N-[(2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide |
| Anwendung: | AMPA receptors positive allosteric modulator |
| CAS | 875927-64-3 |
| MW: | 334.4 D |
ab 153,00 €
