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CAL-101
CAL-101

Artikelnummer: Cay15279-5

The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. CAL-101 is a cell permeable inhibitor of the PI3K catalytic subunit p110delta (IC50 = 2.5 nM) that demonstrates 40- to 300-fold selectivity against other PI3K class I enzymes (IC50s = 820, 565, and...
Schlagworte: Idelalisib, GS-1101, 5-fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone
Anwendung: Cell permeable PIK3CD inhibitor
CAS 870281-82-6
MW: 415.4 D
ab 44,00 €
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Idelalisib, Free Base (CAL-101, GS-1101, Zydelig, CAS 870281-82-6), >99%
Idelalisib, Free Base (CAL-101, GS-1101, Zydelig, CAS...

Artikelnummer: LC-I-7447_25mg

Soluble in DMSO
Schlagworte: Idelalisib, GS-1101, 5-fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone
Anwendung: Cell permeable PIK3CD inhibitor
CAS 870281-82-6
MW: 415,42 D
ab 90,00 €
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CAL101
CAL101

Artikelnummer: LKT-C0044.1

CAL101 is an inhibitor of p110 PI3K that is currently under examination as a potential treatment for leukemias such as mantle cell lymphoma and chronic lymphocytic leukemia (CLL). CAL101 exhibits anticancer chemotherapeutic and immunosuppressive activities. In mantle cell lymphoma cells, CAL101 induces G1 phase...
Schlagworte: Idelalisib, GS1101
Anwendung: PI3K p110 delta inhibitor
CAS 870281-82-6
MW: 415.42 D
ab 84,00 €
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