Zu "870281-82-6" wurden 3 Artikel gefunden!
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Idelalisib
Artikelnummer: TGM-T1894-100mg
Description: Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110delta (IC50: 2.5 nM). The selectivity for p110delta is 40- to 300-fold than p110alpha/beta/gamma. Target: Autophagy, PI3K. Smiles: [C@H](NC1=C2C(N=CN2)=NC=N1)(CC)C=3N(C(=O)C=4C(N3)=CC=CC4F)C5=CC=CC=C5. References:...
| Schlagworte: | CAL-101, GS-1101 |
| Anwendung: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| CAS | 870281-82-6 |
| MW: | 415.42 D |
ab 31,00 €
CAL-101
Artikelnummer: Cay15279-5
The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. CAL-101 is a cell permeable inhibitor of the PI3K catalytic subunit p110delta (IC50 = 2.5 nM) that demonstrates 40- to 300-fold selectivity against other PI3K class I enzymes (IC50s = 820, 565, and...
| Schlagworte: | Idelalisib, GS-1101, 5-fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone |
| Anwendung: | Cell permeable PIK3CD inhibitor |
| CAS | 870281-82-6 |
| MW: | 415.4 D |
ab 45,00 €
CAL101
Artikelnummer: LKT-C0044.1
CAL101 is an inhibitor of p110 PI3K that is currently under examination as a potential treatment for leukemias such as mantle cell lymphoma and chronic lymphocytic leukemia (CLL). CAL101 exhibits anticancer chemotherapeutic and immunosuppressive activities. In mantle cell lymphoma cells, CAL101 induces G1 phase...
| Schlagworte: | Idelalisib, GS1101 |
| Anwendung: | PI3K p110 delta inhibitor |
| CAS | 870281-82-6 |
| MW: | 415.42 D |
ab 88,00 €
