Zu "869363-13-3" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
MLN8054
Artikelnummer: TGM-T6315-100mg
Description: MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM. Target: PKA, Aurora Kinase, Casein Kinase, Src. Smiles: OC(=O)c1ccc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2F)cc1. References: Manfredi MG, et al. Proc Natl Acad Sci U S A, 2007, 104(10), 4106-4111.
| Anwendung: | Aurora A kinase ATP-competitive inhibitor |
| CAS | 869363-13-3 |
| MW: | 476.86 D |
ab 48,00 €
MLN8054
Artikelnummer: Cay27340-1
MLN8054 is an ATP-competitive inhibitor of Aurora A kinase (IC50 = 4 nM). It is selective for Aurora A over Aurora B, PKC, CaMKII, Cdk2E, CK2, LCK, PKA, Chk1, Chk2, Cdk1, and Plk1 (IC50s = 0.172-100 µM). MLN8054 induces cell cycle arrest at the G2/M phase and the formation of abnormal mitotic spindles in HCT116...
| Schlagworte: | 4-[[9-chloro-7-(2,6-difluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-benzoic acid |
| Anwendung: | Aurora A kinase ATP-competitive inhibitor |
| CAS | 869363-13-3 |
| MW: | 476.9 D |
ab 53,00 €
