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ML-351
Artikelnummer: Cay16119-5
Lipoxygenases (LOs) are non-heme iron-containing dioxygenases that catalyze the oxidation of polyunsaturated fatty acids to generate unsaturated fatty acid hydroperoxides. The immediate products of 15-LO fatty acid oxidation act as mediators in inflammation, thrombosis, and cancer. ML-351 is an inhibitor of human...
| Schlagworte: | CID 664510, 5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbonitrile |
| Anwendung: | 15-LO-1 inhibitor |
| CAS | 847163-28-4 |
| MW: | 249.3 D |
ab 77,00 €
ML351
Artikelnummer: TGM-T21902-100mg
Description: ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM). Target: Lipoxygenase. Smiles: CNc1oc(nc1C#N)-c1cccc2ccccc12. References: Rai G, Joshi N, Perry S, et al. Discovery of ML351, a Potent and Selective Inhibitor of Human 15-Lipoxygenase-1. Probe Reports from the...
| CAS | 847163-28-4 |
| MW: | 249.27 D |
ab 48,00 €
