Zu "627536-09-8" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
SD-208
Artikelnummer: TGM-T2109-100mg
Description: SD-208 (ALK5 Inhibitor V), a selective TGF-betaRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity over TGF-betaRII. Target: TGF-beta/Smad. Smiles: Fc1ccc(Cl)cc1-c1nc(Nc2ccncc2)c2nccnc2n1. References: Uhl M, et al. Cancer Res. 2004, 64(21), 7954-7961.
| Schlagworte: | ALK5 Inhibitor V, SD208 |
| Anwendung: | TGFBR1 inhibitor |
| CAS | 627536-09-8 |
| MW: | 352.75 D |
ab 34,00 €
SD 208
Artikelnummer: Cay16619-10
TGF-beta is a cell growth and differentiation factor that has roles in cancer, fibrosis, and numerous other pathologies. TGF-beta signals through two receptor tyrosine kinases, TGF-betaRI and TGF-betaRII. SD 208 is a potent inhibitor of TGF-betaRI kinase (EC50 = 48 nM) that has minimal or no effect at a variety of...
| Schlagworte: | TGF-beta RI Kinase Inhibitor V, 2-(5-chloro-2-fluorophenyl)-N-4-pyridinyl-4-pteridinamine |
| Anwendung: | TGFBR1 inhibitor |
| CAS | 627536-09-8 |
| MW: | 352.8 D |
ab 52,00 €
