Zu "622402-22-6" wurden 2 Artikel gefunden!
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GW 590735
Artikelnummer: Cay10009880-5
The peroxisome proliferator-activated receptors (PPARs) alpha, gamma, and delta are ligand-activated transcription factors that play a key role in lipid homeostasis. Activation of PPARalpha results in increased clearance of triglyceride (TG) rich very low-density lipoprotein (VLDL) via a reduction in plasma levels...
| Schlagworte: | 2-methyl-2-(4-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxamido)methyl)phenoxy)propanoic acid |
| Anwendung: | PPARalpha agonist |
| CAS | 622402-22-6 |
| MW: | 478.5 D |
ab 74,00 €
GW590735, Free Acid
Artikelnummer: LC-G-7322_100mg
Soluble in DMSO. GW590735 is a potent and selective PPARalpha agonist. It stimulated PPARalpha with an EC50 of 4 nM and had at least 500-fold selectivity on PPARalpha versus PPARdelta and PPARgamma. It raised circulating levels of high-density lipoprotein cholesterol. Sierra M.L., et al. 'Substituted...
| Anwendung: | Peroxisome proliferator-activated receptor-alpha (PPAR-alpha) agonist |
| CAS | 622402-22-6 |
| MW: | 478.48 D |
ab 102,00 €
