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Mitotane
Mitotane

Artikelnummer: TGM-T1199-100mg

Description: Mitotane (NCI-C04933) is a derivative of the insecticide DICHLORODI PHENYLDICH LOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression. Target: AChR, Apoptosis....
Schlagworte: Mitotan, NCI-C04933, o,p'-DDD, 2,4'-DDD
Anwendung: Targets steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase (CYP17A)
CAS 53-19-0
MW: 320.04 D
ab 31,00 €
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Mitotane
Mitotane

Artikelnummer: Cay18651-100

Mitotane is an inhibitor of steroidogenesis. It decreases secretion of cortisol (Cay-20739) and 17-hydroxy progesterone (Cay-33154) from H295R adrenocortical carcinoma cells when used at a concentration of 50 µM. Mitotane also inhibits mitochondrial complex IV, also known as cytochrome c oxidase, activity in H295R...
Schlagworte: o,p'-DDD, NSC 38721, 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-benzene
Anwendung: Steroidogenesis inhibitor
CAS 53-19-0
MW: 320 D
ab 44,00 €
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Mitotane
Mitotane

Artikelnummer: LKT-M3576.100

An adrenal cyto-toxic agent used to treat adrenocartical tumors.
Anwendung: Cytotoxic agent
CAS 53-19-0
MW: 320,04 D
ab 101,00 €
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