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Lersivirine
Artikelnummer: TGM-T7700-100mg
Description: Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy. Target: HIV Protease, Reverse Transcriptase. Smiles: CCc1nn(CCO)c(CC)c1Oc1cc(cc(c1)C#N)C#N. References: Davis J, et al. The effect of...
| Schlagworte: | Lersivirine(UK 453061), UK-453061 |
| Anwendung: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 473921-12-9 |
| MW: | 310.35 D |
ab 42,00 €
COVID-19 Forschung
Lersivirine
Artikelnummer: Cay29497-10
Lersivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI, mean IC50 = 118 nM for the wild-type HIV-1 enzyme). It inhibits a panel of 14 single-point mutant HIV-1 reverse transcriptases with mean IC50 values within 10-fold of the wild-type enzyme. Lersivirine inhibits HIV-1 virus replication in MT-2...
| Schlagworte: | UK-453,061, 5-[[3,5-diethyl-1-(2-hydroxyethyl)-1H-pyrazol-4-yl]oxy]-1,3-benzenedicarbonitrile |
| Anwendung: | Antiviral, non-nucleoside reverse transcriptase inhibitor (NNRTI) |
| CAS | 473921-12-9 |
| MW: | 310.4 D |
ab 145,00 €
