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BVT-14225
Artikelnummer: TGM-T3542-100mg
Description: BVT-14225, a selective 11beta-Hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitor, has an IC50 value of 52 nM. Target: Dehydrogenase. Smiles: CCN(CC)C(=O)Cc1csc(NS(=O)(=O)c2cccc(Cl)c2C)n1. References: Barf T, et al. Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs....
| Schlagworte: | BVT 14225 |
| Anwendung: | 11beta-HSD1 inhibitor |
| CAS | 376638-65-2 |
| MW: | 401.93 D |
ab 40,00 €
BVT 14225
Artikelnummer: Cay41224-1
BVT 14225 is an inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1, IC50s = 52 and 284 nM for the human and mouse enzymes, respectively). It is selective for human 11beta-HSD1 over human 11beta-HSD2 (IC50 = >10,000 nM). It inhibits 11beta-HSD1 by 55% in HEK293 cells expressing human HSD11B1, the...
| Schlagworte: | 2-[[(3-chloro-2-methylphenyl)sulfonyl]amino]-N,N-diethyl-4-thiazoleacetamide |
| Anwendung: | 11beta-HSD1 inhibitor |
| CAS | 376638-65-2 |
| MW: | 401.9 D |
ab 35,00 €
