Zu "352693-80-2" wurden 2 Artikel gefunden!
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MMRi62
Artikelnummer: TGM-T60202-100mg
Description: MMRi62 (7-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol), a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity against pancreatic ductal adenocarcinoma (PDAC) cells and induce autophagy. MMRi62...
| Schlagworte: | 7-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol |
| Anwendung: | MDM2 / MDM4 degrader |
| CAS | 352693-80-2 |
| MW: | 396.27 D |
ab 31,00 €
MMRi62
Artikelnummer: Cay40841-10
MMRi62 is a degrader of murine double minute 2 (MDM2) and MDM4. It induces ubiquitination of MDM2 and MDM4 in NALM6 leukemia cells when used at a concentration of 5 µM and selectively decreases the proliferation of MV4-11 leukemia cells (IC50 = ~0.12 µM) over primary human peripheral blood mononuclear cells (PBMCs,...
| Schlagworte: | 7-[(2,3-dichlorophenyl)(2-pyridinylamino)methyl]-8-quinolinol |
| Anwendung: | MDM2 / MDM4 degrader |
| CAS | 352693-80-2 |
| MW: | 396.3 D |
ab 81,00 €
