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GTP-14564
Artikelnummer: TGM-T71857-100mg
Description: GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3. GTP-14564 inhibits the growth of interleukin-3-independent Ba/F1 expressing ITD-FLT3 at 3 µ m, whereas a 30-fold higher concentration of GTP-14564 is required to inhibit the FLT3 ligand-dependent growth (wt-FLT3) of...
| Anwendung: | Class III receptor tyrosine kinase inhibitor |
| CAS | 34823-86-4 |
| MW: | 234.25 D |
ab 40,00 €
GTP 14564
Artikelnummer: Cay17543-1
GTP 14564 is an inhibitor of class III receptor tyrosine kinases (IC50s = 0.3 µM for c-Fms, c-Kit, ITD-FLT3 and 1 µM for PDGFRbeta). It is without effect against a panel of non-receptor tyrosine and serine/threonine kinases. GTP 14564 blocks the proliferation of leukemia cells stimulated with FLT3 ligand by...
| Schlagworte: | 3-phenyl-1H-benzofuro[3,2-c]pyrazole |
| Anwendung: | Class III receptor tyrosine kinase inhibitor |
| CAS | 34823-86-4 |
| MW: | 234.3 D |
ab 44,00 €
