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NSC697923
Artikelnummer: AG-CR1-3519-M005
Synthetic. Selective Ub-conjugating enzyme (E2) complex Ubc13-Uev1A inhibitor. Inhibits the formation of the Ubc13~Ub conjugate. NF-kappaB activation inhibitor. Inhibits proliferation and survival of ABC-DLBCL and GCB-DLBCL (diffuse large B cell lymphoma) cells.
| Schlagworte: | 2-(4-Methylphenyl)sulfonyl-5-nitrofuran |
| Anwendung: | Ubc13-Uev1A inhibitor |
| CAS | 343351-67-7 |
| MW: | 267,3 D |
ab 28,00 €
NSC 697923
Artikelnummer: Cay15346-1
NSC 697923 is a selective inhibitor of the E2 ubiquitin-conjugating enzyme Ubc13 when heterodimerized with Uev1A, blocking polyubiquitin chain formation at concentrations of 0.5 to 2 µM in vitro. It also inhibits NF-kappaB activation by PMA and other agonists, presumably through its effects on Ubc13. NSC 697923...
| Schlagworte: | 2-[(4-methylphenyl)sulfonyl]-5-nitro-furan |
| Anwendung: | Ubc13 inhibitor |
| CAS | 343351-67-7 |
| MW: | 267.3 D |
ab 31,00 €
