Zu "328087-38-3" wurden 2 Artikel gefunden!
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Phortress
Artikelnummer: Cay15342-5
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. Phortress is a lysyl amide prodrug of the benzothiazole 5-fluoro 203...
| Schlagworte: | NSC 710305, 2S,6-diamino-N-[4-(5-fluoro-2-benzothiazolyl)-2-methylphenyl]-hexanamide, dihydrochloride |
| Anwendung: | AhR ligand prodrug |
| CAS | 328087-38-3 |
| MW: | 459.4 D |
ab 133,00 €
Phortress
Artikelnummer: TGM-T23151-100mg
Description: Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor activity. Target: AhR. Smiles: CC1=C(NC([C@@H](N)CCCCN)=O)C=CC(C2=NC3=CC(F)=CC=C3S2)=C1.Cl.Cl. References: Bradshaw TD, et al. In vitro evaluation of...
| Schlagworte: | NSC 710305 |
| CAS | 328087-38-3 |
| MW: | 459.41 D |
ab 31,00 €
